Association Between Total Body Composition And VO2max In Individuals With Mid-spectrum Chronic Kidney Disease

Total body composition (TBC), a measure of fat percentage (%BF), lean mass (LBM), and bone mineral content (BMC), can be used as predictor cardiovascular fitness. Prior studies have established relationship between TBC VO2max in healthy individuals over 35 years age. However, this is poorly understood chronic disease populations. PURPOSE: To assess the fitness clinical population adults with mid-spectrum (stages G2, G3a, G3b) kidney (CKD). METHODS: A cross-sectional analysis was conducted among 24 subjects diagnosed CKD. Nine males 15 females an average age 62.25 ± 9.2 glomerular filtration rate (GFR) 54.38 9.04 ml/min/1.73m2 completed study. Subjects health screening, dual-energy x-ray absorptiometry (DEXA) scan, underwent testing on treadmill using modified Bruce protocol. Normality tests, descriptive statistics, Pearson’s correlations, t-tests, ANOVAs were SAS v.9.4. RESULTS: The %BF 36.28 8.47%, LBM 117.16 31.32lbs., BMC 2308.74 735.19 g., 20.13 5.04 ml/kg/min. positively correlated (r = 0.65, p 0.001 r 0.75, < 0.001, respectively) negatively -0.80, 0.001). Individuals later stages CKD had lower LBM, BMC, (p 0.017, 0.007, respectively), yet there no association stage or 0.210 0.107). CONCLUSION: found to significantly associated study sample. Higher BMD values higher whereas Progression values, indicating graded effect